Uniapnea

Tutkimus ja tutkimustulokset

Uniapneaa ja sen oireita, riskejä sairastua muihin sairauksiin, onnettomuusalttiutta ja hoitoa koskevia tutkimuksia on melko paljon. Useimmat tutkimukset on tehty ulkomailla, missä myös uniapneaan liittyvät ongelmat tunnetaan paremmin. Olemme keräänneet alle joukon keskeisiä ruotsalaisia uniapneaa koskevia tutkimustuloksia.

 

Uniapnean prevalenssi (esiintyminen) ja erot eri sukupuolten välillä
Larsson LG, Lindberg A, Franklin KA, Lundback B. Gender differences in symptoms related to sleep apnea in a general population and in relation to referral to sleep clinic. Chest. 2003 Jul;124(1):204-11.


Liikenne

Carter N, Ulfberg J, Nystrom B, Edling C. Sleep debt, sleepiness and accidents among males in the general population and male professional drivers. Accid Anal Prev. 2003 Jul;35(4):613-7
Haraldsson PO, Akerstedt T. Drowsiness--greater traffic hazard than alcohol. Causes, risks and treatment. Lakartidningen. 2001 Jun 20;98(25):3018-23.
Akerstedt T, Haraldsson PO. International consensus meeting on fatigue and the risk of traffic accidents. The significance of fatigue for transportation safety is underestimated Lakartidningen. 2001 Jun 20;98(25):3014-7.
Haraldsson PO, Carenfelt C, Tingvall C. Sleep apnea syndrome symptoms and automobile driving in a general population. J Clin Epidemiol. 1992 Aug;45(8):821-5.
Haraldsson PO, Carenfelt C, Diderichsen F, Nygren A, Tingvall C. Clinical symptoms of sleep apnea syndrome and automobile accidents. ORL J Otorhinolaryngol Relat Spec. 1990;52(1):57-62.


Työpaikka
Ulfberg J, Carter N, Edling C. Sleep-disordered breathing and occupational accidents. Scand J Work Environ Health. 2000 Jun;26(3):237-42.
Ulfberg J, Jonsson R, Edling C. Improvement of subjective work performance among obstructive sleep apnea patients after treatment with continuous positive airway pressure. Psychiatry Clin Neurosc. 1999 Dec;53(6):677-9.
Ulfberg J, Carter N, Talback M, Edling C. Excessive daytime sleepiness at work and subjective work performance in the general population and among heavy snorers and patients with obstructive sleep apnea. Chest. 1996 Sep;110(3):659-63.


Kuorsaus ja päänsärky

Ulfberg J, Carter N, Talback M, Edling C. Headache, snoring and sleep apnoea. J Neurol.1996 Sep;243(9):621-5.


Sydän- ja verisuonisairaudet
Hedner J, Bengtsson-Bostrom K, Peker Y, Grote L, Rastam L, Lindblad U. Hypertension prevalence in obstructive sleep apnoea and sex: a population-based case-control study. Eur Respir J. 2006 Mar;27(3):564-70.
Peker Y, Grote L, Kraiczi H, Hedner J. Sleep apnea a risk factor of cardiovascular disease Lakartidningen. 2002 Nov 7;99(45):4473-9.
Peker Y, Hedner J, Norum J, Kraiczi H, Carlson J. Increased incidence of cardiovascular disease in middle-aged men with obstructive sleep apnea: a 7-year follow-up. Am J Respir Crit Care Med. 2002 Jul 15;166(2):159-65.
Kraiczi H, Peker Y, Caidahl K, Samuelsson A, Hedner J. Blood pressure, cardiac structure and severity of obstructive sleep apnea in a sleep clinic population. J Hypertens. 2001 Nov;19(11):2071-8.
Peker Y, Hedner J, Kraiczi H, Loth S. Respiratory disturbance index: an independent predictor of mortality in coronary artery disease. Am J Respir Crit Care Med. 2000 Jul;162(1):81-6.
Peker Y, Kraiczi H, Hedner J, Loth S, Johansson A, Bende M. An independent association between obstructive sleep apnoea and coronary artery disease. Eur Respir J. 1999 Jul;14(1):179-84.
Peker Y, Hedner J, Johansson A, Bende M. Reduced hospitalization with cardiovascular and pulmonary disease in obstructive sleep apnea patients on nasal CPAP treatment. Sleep. 1997 Aug;20(8):645-53.
Franklin KA. Cerebral haemodynamics in obstructive sleep apnoea and Cheyne-Stokes respiration. Sleep Med Rev. 2002 Dec;6(6):429-41.
Mooe T, Franklin KA, Holmstrom K, Rabben T, Wiklund U. Sleep-disordered breathing and coronary artery disease: long-term prognosis. Am J Respir Crit Care Med. 2001 Nov 15;164(10 Pt 1):1910-3.
Mooe T, Rabben T, Wiklund U, Franklin KA, Eriksson P. Sleep-disordered breathing in men with coronary artery disease. Chest. 1996 Mar;109(3):659-63.
Franklin KA, Nilsson JB, Sahlin C, Naslund U. Sleep apnoea and nocturnal angina. Lancet. 1995 Apr 29;345(8957):1085-7.
Mooe T, Rabben T, Wiklund U, Franklin KA, Eriksson P. Sleep-disordered breathing in women: occurrence and association with coronary artery disease. Am J Med. 1996 Sep;101(3):251-6.
Grote L, Hedner J, Peter JH. Sleep-related breathing disorder is an independent risk factor for uncontrolled hypertension. J Hypertens. 2000 Jun;18(6):679-85.
Becker HF, Jerrentrup A, Ploch T, Grote L, Penzel T, Sullivan CE, Peter JH. Effect of nasal continuous positive airway pressure treatment on blood pressure in patients with obstructive sleep apnea. Circulation. 2003 Jan 7;107(1):68-73.
Grote L, Ploch T, Heitmann J, Knaack L, Penzel T, Peter JH. Sleep-related breathing disorder is an independent risk factor for systemic hypertension. Am J Respir Crit Care Med. 1999 Dec;160(6):1875-82.
Leineweber C, Kecklund G, Akerstedt T, Janszky I, Orth-Gomer K. Snoring and the metabolic syndrome in women. Sleep Med. 2003 Nov;4(6):531-6.Grote L, Hedner J, Peter JH. Mean blood pressure, pulse pressure and grade of hypertension in untreated hypertensive patients with sleep-related breathing disorder. J Hypertens. 2001 Apr;19(4):683-90
Hedner J, Grote L. The Link between Sleep Apnea and Cardiovascular Disease. Time to Target the Nonsleepy Sleep Apneics? Am. J. Respir. Crit. Care Med., Volume 163, Number 1, January 2001, 5-6


Respiraatio ja hengitys
Larsson LG, Lindberg A, Franklin KA, Lundback B; Obstructive Lung Disease in Northern Sweden Studies. Obstructive sleep apnoea syndrome is common in subjects with chronic bronchitis. Report from the Obstructive Lung Disease in Northern Sweden studies. Respiration. 2001;68(3):250-5.


CPAP-hoito
Grunstein RR, Hedner J, Grote L. Treatment options for sleep apnoea. Drugs. 2001;61(2):237-51.




Mediassa
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Kuorsaus on tavallinen uniapnean oire, samoin kuin täysin äänettömät jaksot. Voit kuunnella esimerkin siitä, miltä uniapneasta kärsivä henkilö voi kuulostaa.

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